Antioxee – Boost anti-oxidant support and gut microbiome health

$38.49

Antioxee contains pomegranate skin and seed extract that is rich in Ellagitannins along with other phenolic acids, anthocyanins, hydrolyzable tannins, and tocophenols. This acts as a prebiotic for our proprietary blend of Lactobacillus bacteria*.

Inclusion of these probiotic bacteria, naturally found in a healthy human lower intestinal tract or lower gut, along with Pomegranate extract will improve the bioconversion of the active ingredients in the fruit extract to the bioavailable form of antioxidants. Our product is aimed at aiding the metabolic conversion of Ellagitannins in the fruit extract to Ellagic Acid (EA) which is easily metabolized by the GI microbes to Urolithin*.

Since these are essential probiotic bacteria from our gut microbiome, these are also known to colonize better in the presence of the fruit ingredients and reduce the presence of many harmful bacteria*.

Description

Just 1 capsule a day (or your physician’s recommendation) is all it takes to experience the benefits of Antioxee*! Each day, you’ll experience better antioxidant support, nutrient absorption, and long term improvement of mental health. 

ANTIOXEE is aimed at aiding the metabolic conversion of Ellagitannins in the fruit extract to Ellagic Acid (EA) which is easily metabolized by the GI microbes to Urolithin, the form of antioxidant that our body can absorb. The pomegranate skin and seed extract is rich in Ellagitanins along with other phenolic acids, anthocyanins, hydrolyzable tanins and tocophenols. This acts as a prebiotic for our proprietary blend of Lactobacillus bacteria.

We all know antioxidants are important for our health. We eat antioxidant-rich fruits, nuts and vegetables. Numerous research has shown that antioxidants from our food have several beneficial effects:

They improve the function of our mitochondria, powerhouse of our body. Thus we get energy boost. Antioxidants (Urolithin B) have been shown to improve muscle function.

These antioxidants have been shown to upregulate Nrf2 gene, a master regulator of detoxification pathway. 1

Ellagic acid from antioxidant-rich food along with other chemical compounds present in them have been shown to have pronounced anti-inflammatory effect.2

Numerous research have shown a direct correlation between antioxidants and anti-cancer activity.3,4

Peer reviewed research has also shown key mechanism by which pomegranate fractions affect the type 2 diabetic condition by reducing oxidative stress and lipid peroxidation. 5

 

But, many of us do not realize that the antioxidants present in fruits like pomegranate, cranberries and strawberries are not fully available to our body. These fruits are rich in Ellagitanins, which are poorly absorbed by our body.6

This Ellagtanin is converted to Ellagic acid by bacteria in our gut. The Ellagic acid is then easily converted to Urolithin by gut bacteria. This Urolithin is what is absorbed by our body as the beneficial and functional form of anti-oxidant.

Further, pomegranate extracts have other health benefits along with being a source of Ellagic Acid.7

 

Science Behind Our Strains

1Acta Physiologica Sinica Study: How Urolithin B increases detoxification, antioxidant, and anti-inflammatory benefits.

2BMC Complement Altern Study: Anti-inflammatory potential of pomegranate tannin extract in combination with other polyphenols as found in pomegranate juice.

3The Journal of Nutritional Biochemistry Volume 16, Issue 6, June 2005, Pages 360-367                                                                               

4Molecular Cancer Therapeutics February 2019 Volume 18, Issue 2 

5Pomegranate and Type 2 Diabetes

6 Cristina Garcia-Muñoz & Fabrice Vaillant (2014) Metabolic Fate of Ellagitannins: Implications for Health, and Research Perspectives for Innovative Functional Foods, Critical Reviews in Food Science and Nutrition, 54:12, 1584-1598, DOI: 10.1080/10408398.2011.644643

7 Front Microbiol. 2019; 10: 660. Published online 2019 Apr 3. doi: 10.3389/fmicb.2019.00660 PMCID: PMC6456667 PMID: 31001233

Beneficial Effects of Pomegranate Peel Extract and Probiotics on Pre-adipocyte Differentiation

Valeria Sorrenti,1,* Cinzia Lucia Randazzo,2 Cinzia Caggia,2 Gabriele Ballistreri,3 Flora Valeria Romeo,3 Simona Fabroni,3 Nicolina Timpanaro,3 Marco Raffaele,1 and Luca Vanella1

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. It is recommended that a physician be consulted before taking any supplements. Results not typical and may vary.

This product has not been specifically tested to comply with California Prop-65

Additional information

Weight 0.5 lbs
Dimensions 4 × 3 × 2.5 in

Supplement Facts

Serving size: 1 Caplet
Servings per container: 30


Amount per Serving                                                                             


Proprietary Probiotic Blend                                         175 mg†

Lactobacillus plantarum SD5870        1 Billion CFU*†

Lactobacillus rhamnosus DSM 6594   1 Billion CFU * †

Proprietary Blend                                                            

Pomegranate extract (skin) Ellagic Acid)          100 mg†

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Pectin, Silicon Carbonate, Stearic Acid, Sodium dioxide


* CFU – Available Colony Forming Unit at the end of 24 months expiry period.

† Daily value not established

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